Tuesday, 8 August 2017

Orthobiologics Market - Global Industry Analysis, Size, Share, Growth and Forecast Report To 2025





Orthobiologics helps to heal injured muscles, fractures, tendons and ligaments more quickly. These are made up of naturally occurring body substances such as autologous conditioned serum, autologous blood, bone grafts, stem cells, platelet rich plasma, and growth factors. Therefore, these are commercially available for orthopedic applications such as joint reconstruction, spinal fusion, and sports related injuries.
Rise in number of orthopedic surgeries, rapidly aging population, increasing in adoption of advanced products, and growing demand for minimal invasive procedures are set to drive the global market for orthobiologics. As per the report published by American Academy of Orthopedic Surgeons, in U.S., around 500,000 bone grafting surgeries are performed every year. Of these, almost half of the surgeries are related to spinal fusion. These large number of procedures lead to rise in demand for musculoskeletal tissue donation and a shortage of cadaver material.
Additionally, increased availability of products with high osteoinductive and osteoconductive properties will further contribute to the market growth. An osteoinductive protein provides biophysical stimulation which helps to repair and regenerate bone fractures. Moreover, the high demand for orthobiologics in orthopedic industry coupled with rise in adoption of orthobiologics in different orthopedic applications such as joint reconstruction, trauma, craniomaxillofacial, and spinal fusion.
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Development of novel products related to bone healing has changed the field of orthopedic treatment. Therefore, major players are highly focused on developing and commercializing technologically advanced products. For instance, in September 2015, Wright Medical Group Inc. obtained premarket approval for its Augment bone graft from FDA. This graft can be used in ankle or hind foot fusion procedures. Similarly, in November 2015, CeraPedics, an orthobiologics company, obtained Premarket Approval (PMA) application for its “i-FACTOR Peptide Enhanced Bone Graft”. This graft can be used for the treatment of degenerative cervical disc related disorders. Thus, introduction of technologically advanced products is set to propel the market growth.
Major players operating in this market are Medtronic plc, Stryker Corporation, Bone Biologics Corp., Orthofix, Inc., Arthrex, Inc., Isto Biologics, Bioventus, NuVasive, Inc., Osiris Therapeutics, Inc., and RTI Surgical, Inc. These companies are highly focused on expanding their geographical presence through establishing strong distribution channels and direct sales network.
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Capsule Endoscopy Market - Global Industry Analysis, Size, Share, Growth and Forecast Report To 2025




Capsule endoscopy is a minimal invasive procedure in which a tiny camera is used to capture images of patient’s digestive tract. It is a shape and size of a pill containing a tiny camera. The Capsule capture pictures of the digestive tract once the patient swallows it. It provides high resolution images which cannot be taken by any other endoscopy. Capsule endoscopy has witnessed significant technological advancements (such as image resolution, battery life, and miniaturization of the device) since its introduction to the market.
The capsule endoscopy market is projected to witness robust growth during the forecast period, primarily due to growing prevalence of gastrointestinal (GI) tract diseases, rapidly aging population, growing popularity of minimally invasive procedures, and technological advancements. Moreover, high preference for capsule endoscopy for GI procedures due to its minimal invasive nature will further contribute to the market growth.
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The rapidly aging population is set to drive the demand for capsule endoscopes as this group is more susceptible to GI diseases. As per Health Guidance for Better Health, almost 34 million people are affected with digestive tract diseases in the U.S., of which 20 million Americans have chronic condition. It further states that around 8% of the total population in the U.S. suffers from chronic digestive tract disorders, 6% from acute disorders, and 43% from intermittent GI disorders. Moreover, the growing elderly population will further contribute to the market growth. For instance, the number of older people is projected to reach 2 billion in 2050 from 841 million people in 2013 (Source: United Nations Department of Economic and Social Affairs). Thus, the rapidly aging population will accelerate the demand for capsule endoscopy in near future. Such high target population will bring in ample growth opportunities for the key players to develop technologically advanced products.
In addition to this, the rising prevalence of colon cancer will further stimulate the market growth. For instance, in 2012, the estimated number of colon cancer cases was 1.4 million and this number is expected to reach 2.4 million by 2035. Therefore, a large patient pool of colon cancer will be in need of adequate diagnostic and monitoring devices such as capsule endoscopes.
Major players operating in this market are IntroMedic Co. Ltd., Olympus Corporation, SynMed Limited, CapsoVision Inc., Fujifilm Holding Corporation, and Given Imaging Ltd. These companies are highly focused on introduction of new capsule endoscopes with innovative techniques and advanced features to meet the unmet medical needs. Thus, innovation will derive the demand for capsule endoscopes globally.
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Crystal Market Research is a U.S. based market research and business intelligence company. Crystal offers one stop solution for market research, business intelligence, and consulting services to help clients make more informed decisions. It provides both syndicated as well as customized research studies for its customers spread across the globe. The company offers market intelligence reports across a broad range of industries including healthcare, chemicals & materials, technology, automotive, and energy.
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Drug Device Combination Market Analysis- Products, Application - Forecast Report To 2025





Drug device combination is combining two or more different types of products including medical devices, biologics and drugs. With drug device combination products there is an increase in overall efficacy and percentage of patients who respond. The efficacy depends upon the pharmacodynamics and pharmacokinetic properties of the drug used in combination. There are different types of drug device combination products. In case of infusion pumps, fluids such as nutrients and medications are administered into a patient’s body in controlled amounts. Next drug device combination product is inhaler which helps in administering drug to a patient via lungs. Further, transdermal patch is an adhesive pad which is placed on skin to administer a time released dose of medication directly into the bloodstream via skin. In case of drug eluting stents such as urethral stents, the stent is coated with medicines such as heparin which is an anti-coagulating agent. This stent maintains the urinary flow from the kidney to the bladder while avoiding coagulation. Another drug device combination product is orthopedic drug combination product such as antibiotic bone cement which is used for treating infected joint arthroplasties. Next combination product is drug device combination, in which duration of action of a drug and intensity is increased. It reduces the dosage frequency and improves patient compliance. Wound care products are used in managing wounds. In case of photodynamic therapy devices, a photosensitizer and a type of light is used to treat tumors on the skin.
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The major factor driving the growth of drug devices market is increase in the prevalence of chronic diseases. According to European Academy of Allergy and Clinical Immunology (EAACI), in 2013, around 300 million people were suffering from asthma and the number is expected to increase by 100 million by 2025. In terms of global years lived with disability, the Global Asthma Network states that asthma is the 14th most important medical condition worldwide. Further, it also states that, asthmatic symptoms are experienced by 14% of the total children population across the world. Additionally, increase in the adoption of point of care treatments will also boost this market. Moreover, increase in the geriatric population will also drive this market. For instance, according to WHO, in 2015, 900 million people were 60 years of age or older and the number is expected to reach up to 2 billion by 2050.
The key strategy followed by the major players in the drug device combination market is product launch to gain competitive advantage and more market share. For instance, in 2016, AstraZeneca’s Bevespi Aerosphere was approved by the FDA for patients with COPD. It is a metered dose inhaler which contains combination of two drugs, namely, glycopyrrolate and formoterol fumarate. With the launch of this drug AstraZeneca will gain competitive advantage and more share in the market.
The major players in the drug device market are Medtronic, Terumo Corporation, W. L. Gore & Associates, Inc., C.R. Bard, Inc., Johnson & Johnson Private Limited, Stryker Corporation, Medline, Medtronic, Mylan Inc., and, Becton, Dickinson and Company, and Pinnacle Biologics.
About Crystal Market Research
Crystal Market Research is a U.S. based market research and business intelligence company. Crystal offers one stop solution for market research, business intelligence, and consulting services to help clients make more informed decisions. It provides both syndicated as well as customized research studies for its customers spread across the globe. The company offers market intelligence reports across a broad range of industries including healthcare, chemicals & materials, technology, automotive, and energy.
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Thursday, 3 August 2017

Sacral Nerve Stimulation Market Analysis- Products, Application - Forecast Report To 2025




Sacral Nerve Stimulation (SNS) is an electrical stimulation therapy for the treatment of bladder control and bowel control symptoms. A programmable stimulator is implanted subcutaneously to deliver electrical stimulation through a lead to the sacral nerve. This is a clinically proven treatment for overactive bladder (OAB) patients which significantly improve quality of life as compared to patients on therapeutics.
OAB is one of the most common condition affecting millions of people worldwide. Sudden urge to urinate is the most common symptom of OAB. This urge is difficult to stop and hence leads to involuntary leaking of urine (known as incontinence). OAB affects 85 million adults in Europe and the U.S. and 40 million people are suffering from fecal incontinence. Over the past two decades, this therapy has been widely adopted in the U.S. and Europe for the treatment of OAB, primarily due to availability of favorable reimbursement.
Rise in prevalence of OAB symptoms coupled with rapidly aging population, increased research and development (R&D) efforts by SNS manufacturers, and technological advancements in SNS systems are set to boost the adoption of SNS systems. However, side-effects associated with SNS systems will hinder the market growth. But, the development of O-arm guided navigation systems, and antibacterial and bioabsorbable technology are the current industry trends, which will bring in huge growth opportunities for the manufacturers.
Moreover, innovation is set to derive the demand for sacral neuromodulation systems globally. Therefore, major players emphasize on new product development in order to gain competitive advantage. For instance, in January 2017, Axonics Modulation Technologies, Inc. obtained approval from Health Canada for its rechargeable Sacral Neuromodulation (r-SNM) System, which is designed for the treatment of overactive bladder, urinary retention, and fecal incontinence. Likewise, in February 2017, Nuvectra Corporation filed regulatory submissions for CE mark and FDA approvals for its Virtis Sacral Nerve Stimulation System. This system can be used to treat overactive bladder and chronic urinary retention. Thus, development of such innovative SNS systems to meet the unmet medical needs will further contribute to the market growth.
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Additionally, increased research and development (R&D) efforts is one of the key drivers for the growth of this market. In line with this strategy, major companies are raising finances for conducting studies on SNS systems. For instance, in May 2017, Axonics Modulation Technologies, Inc. obtained $14.5 million for a pivotal study of its neuromodulation system in overactive bladder patients. Further, it aims to raise $30 million to kick off its U.S. pivotal study, which is expected to be conducted in Europe and the U.S. Prior to this, the company has received $38.5 million for its SNS system.
Some of the major players operating in this market are Axonics Modulation Technologies, Inc, Medtronic plc, and Nuvectra Corporation. Medtronic has monopoly in the global SNS Market. The company has strong product portfolio of both external and implantable SNS devices. It offered innovative treatments to around 225,000 patients globally through its InterStim system.  
About Crystal Market Research
Crystal Market Research is a U.S. based market research and business intelligence company. Crystal offers one stop solution for market research, business intelligence, and consulting services to help clients make more informed decisions. It provides both syndicated as well as customized research studies for its customers spread across the globe. The company offers market intelligence reports across a broad range of industries including healthcare, chemicals & materials, technology, automotive, and energy.
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